diff --git a/Lib/test/test_bytes.py b/Lib/test/test_bytes.py
index 5d4f2155a6b065..69235d444b915e 100644
--- a/Lib/test/test_bytes.py
+++ b/Lib/test/test_bytes.py
@@ -2571,10 +2571,6 @@ def iconcat(b, a):  # MODIFIES!
             b.wait()
             a += c
 
-        def irepeat(b, a):  # MODIFIES!
-            b.wait()
-            a *= 2
-
         def subscript(b, a):
             b.wait()
             try: assert a[0] != 0xdd
@@ -2696,9 +2692,10 @@ def check(funcs, a=None, *args):
 
         check([clear] + [repeat] * 10)
         check([clear] + [iconcat] * 10)
-        check([clear] + [irepeat] * 10)
         check([clear] + [ass_subscript] * 10)
         check([clear] + [repr_] * 10)
+        # gh-148605: Do not test "a *= 2" since it allocates up to 4 GiB using
+        # 10 threads
 
         # value errors